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Organic Chemistry

Copper-Catalyzed Asymmetric Synthesis by Alexandre Alexakis,Norbert Krause,Simon Woodward

By Alexandre Alexakis,Norbert Krause,Simon Woodward

This booklet displays the expanding curiosity one of the chemical artificial group within the quarter of uneven copper-catalyzed reactions, and introduces readers to the most recent, most vital advancements within the field.

The contents are prepared in response to response variety and canopy mechanistic and spectroscopic facets in addition to functions within the synthesis of usual items. a complete bankruptcy is dedicated to figuring out how basic organometallics have interaction with copper to supply selective catalysts for allylic substitution and conjugate addition, either one of that are handled in separate chapters. one other is dedicated to the diversity of substrates and experimental protocols, whereas a whole bankruptcy covers the use on non-carbon nucleophiles. different chapters take care of less-known reactions, corresponding to carbometallation or the additions to imines and comparable platforms, whereas the extra tested reactions cyclopropanation and aziridination in addition to using copper (II) Lewis acids are warranted their very own detailed chapters. extra chapters quandary the approaches concerned, as decided via mechanistic reviews. eventually, an entire bankruptcy is dedicated to the unreal applications.

this can be crucial examining for researchers at educational associations and pros at pharmaceutical or agrochemical companies.

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