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Industrial Technical Chemistry

Antibacterial Agents: Chemistry, Mode of Action, Mechanisms by Rosaleen Anderson,Paul Groundwater,Adam Todd,Alan Worsley

By Rosaleen Anderson,Paul Groundwater,Adam Todd,Alan Worsley

Antibacterial brokers act opposed to bacterial an infection both through killing the bacterium or by way of arresting its progress. They do that through concentrating on bacterial DNA and its linked techniques, attacking bacterial metabolic methods together with protein synthesis, or interfering with bacterial mobilephone wall synthesis and function.

Antibacterial Agents is an important consultant to this significant category of chemotherapeutic medications. Compounds are organised based on their goal, which is helping the reader comprehend the mechanism of motion of those medicines and the way resistance can come up. The ebook makes use of an built-in “lab-to-clinic” strategy which covers drug discovery, resource or synthesis, mode of motion, mechanisms of resistance, scientific features (including hyperlinks to present directions, major drug interactions, cautions and contraindications), prodrugs and destiny improvements.

Agents lined include:

  • agents concentrating on DNA - quinolone, rifamycin, and nitroimidazole antibacterial agents
  • agents focusing on metabolic tactics -  sulfonamide antibacterial brokers and trimethoprim
  • agents concentrating on protein synthesis - aminoglycoside, macrolide and tetracycline antibiotics, chloramphenicol, and oxazolidinones
  • agents concentrating on mobile wall synthesis - β-Lactam and glycopeptide antibiotics, cycloserine, isonaizid, and daptomycin

Antibacterial Agents will discover a position at the bookshelves of scholars of pharmacy, pharmacology, pharmaceutical sciences, drug design/discovery, and medicinal chemistry, and as a bench reference for pharmacists and pharmaceutical researchers in academia and industry.

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